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Creative BioMart

Antibody/Protein Aggregation Assay Kit | Creative BioMart

Antibody and protein aggregation are important issues in the field of Biotherapeutics. A wide range of conditions and different stages of processing of biopharmaceuticals, such as, formulation, purification, storage, shipping and handling, heat, freeze thaw cycles, mechanical stress, chemical trea;ent etc. might cause aggregation of proteins, enzymes and antibody targets. The possibility of protein aggregates in eliciting immunogenicity is a major concern for biotherapeutics, which might compromise the safety and efficacy of the biologically derived drug products. Recombinant protein production and storage would highly benefit from a high throughput screening method that can screen a variety of formulation and storage conditions of a particular target proteintibody. Currently, different biophysical techniques such as Dynamic Light Scattering (DLS), Size-exclusion Chromatography with Multi-angle Light Scattering (SEC-MALS) can detect the presence of small amount of aggregates in a proteintibody preparation, but they are not amenable for high-throughput screening format. Antibody/Protein Aggregation assay kit is a platform to estimate the extent of aggregation within a proteintibody sample. This is a fast, high-throughput, plate-based fluorometric assay format and can detect as low as 0.5% antibody aggregate.

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ABOUT THE COMPANY

Creative BioMart is a professional biotechnology supplier focused on the development and production of recombinant protein products. Over the years, we have grown exponentially to offer over 100,000 protein products, including recombinant protein, native proteins, cell/tissue lysates, chromatography, lectins, and detection kits. In response to customers'...
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