Companies / Santa Cruz Biotechnology / Pim-1 (12H8) Alexa Fluor® 790
Santa Cruz Biotechnology

Pim-1 (12H8) Alexa Fluor® 790 | Santa Cruz Biotechnology

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mouse monoclonal IgG1; Pim-1 Antibody (12H8) is an IgG1 κ mouse monoclonal Pim-1 antibody that detects Pim-1 of mouse, rat and human origin by WB and IP. Pim-1 Antibody (12H8) is available as both conjugated and non-conjugated anti-Pim-1 antibody forms. Pim-1 is a serine/threonine kinase that cooperates with c-Myc in lymphoid cell transformation. The expression of pim-1 increases during the progression from early to late G1, remaining high at the G1/S boundary and G2 phases of the cell cycle. Pim-1 is regulated at both the transcriptional and translational level, and it has been shown to be induced by IL-2 stimulation. Pim-1 also plays a role in T cell differentiation, and it has been shown to stimulate c-Myc-mediated apoptosis upstream of caspase-3-like proteases.

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Santa Cruz Biotechnology

Santa Cruz Biotechnology is a world leader in the development of products for the biomedical research market. Over the past 30+ years, the Company has focused on the ongoing development of research antibodies, siRNA and CRISPR Gene editing tools, biochemicals, labware and more recently has expanded into animal health care products. Santa Cruz Biotechnology has the highest commitment to quality and customer service.

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