mouse monoclonal IgG1; Pim-2 Antibody (1D12) is an IgG1 κ mouse monoclonal Pim-2 antibody (also designated Pim-2 antibody) that detects the Pim-2 protein of mouse, rat and human origin by WB, IP, IF and IHC(P). Pim-2 Antibody (1D12) is available as both the non-conjugated anti-Pim-2 antibody form, as well as multiple conjugated forms of anti-Pim-2 antibody, including agarose, HRP, PE, FITC and multiple Alexa Fluor® conjugates. The pim-2 gene product (provirus integration site for Moloney murine leukemia virus), is a serine/threonine kinase that is capable of autophosphorylation. Human transcripts for pim-2 have been detected in hematopoietic lineages as well as leukemic and lymphomic cells (K-562, HL-60, RAJI, SW480, testis, small intestine, and colon). Additionally, Pim-2 kinase is found at moderate levels and is distributed evenly throughout the brain. Pim-2 kinase is implicated in tumor phenotypes and may be involved in the formation and preservation of Long-Term Potentiation (LTP), a profuse, activity-dependent enhancement of synaptic efficacy that is implicated in long-term memory.