mouse monoclonal IgG1; apoB Antibody (C1.4) is an IgG1 κ mouse monoclonal apoB antibody (also designated Apolipoprotein B antibody) that detects the apoB protein of human origin by WB, IP, IF, IHC(P) and ELISA. apoB Antibody (C1.4) is available as both the non-conjugated anti-apoB antibody form, as well as multiple conjugated forms of anti-apoB antibody, including agarose, HRP, PE, FITC and multiple Alexa Fluor® conjugates. Post-transcriptional editing of apolipoprotein B (apoB) mRNA is regulated by APOBEC1 (also designated human (or rat) small intestinal apolipoprotein B mRNA editing protein, HEPR, or REPR) in hepatic cells to achieve a steady state proportion of edited and unedited RNA molecules. Two forms of apoB are known to circulate in the plasma of mammals. apoB-100 is a protein primarily synthesized in the liver as a structural component of very-low-density lipoprotein particles. A truncated form of apoB-100, apoB-48, is synthesized in the small intestine and contains the amino-terminal 2,152 amino acids of the larger protein. This organ-specific partitioning of apoB production is the result of RNA editing of a common apoB gene.