Labroots and the Drug Discovery planning committee are pleased to announce its 6th annual event in the Drug Discovery & Development Virtual Event Series....
The Human Neutrophil Lipocalin (HNL) also called NGAL, Lipocalin 2 etc. is produced by and secreted from epithelial cells and neutrophil granulocytes. In blood HNL exists in several molecula...
Novel immunotherapy has revolutionized the landscape of cancer therapy in multiple tumor types since Ipilimumab, the first ICB agent, was approved for the treatment of metastatic melanoma is...
Novel annotated Patient-Derived tumor Xenografts (PDX) propagated in immunodeficient mice and Organoids (PDO) in Matrigel have become essential models to study inter- and intra-tumor heterog...
Advances in tissue-based technologies over the past few years have created opportunities to identify patterns that can be used as biomarkers and prognostic indicators for different disease s...
Marine organisms produce a wide variety of primary and secondary metabolites with unique scaffolds that are biologically active. Manzamines are marine-derived polycyclic alkaloids. Approxima...
In this project, we optimized a high-throughput fluorescent-based assay to assess transporter activity by measuring uptake of the substrate, ASP+ 4-(4-(dimethylamino)styryl)-N-methylpyridi...
G Protein Coupled Receptors (GPCRs) are therapeutic targets for many medications used to treat a variety of disease states. A large number of genetic variants have been identified in the gen...
Learning Objectives: 1. Describe and discuss some of the unique aspect of in vivo studies. 2. Identify specific study practices to ensure high quality study data and animal welfare. 3. Discu...
Non-alcoholic fatty liver disease (NAFLD) is a spectrum of metabolic disorders affecting 25% of our global population. 20% of NAFLD patients go on to develop Non-alcoholic steatohepatitis (N...
Ninety percent of therapeutic agents reaching clinical trial fail to reach entry to market, with safety concerns being a major cause for failures in phase I and II clinical trials. Drug-indu...
Date: February 21, 2023 Time: 10:00am (PST), 1:00pm (EST), 7:00pm (CET) The use of algorithms that alter patient medical care based on race has fallen under increasing criticism, as race-bas...
Date: February 21, 2023 Time: 8:00am (PST), 11:00am (EST), 5:00pm (CET) Cancer is a highly heterogeneous disease in need of accurate and non-invasive diagnostic tools. Here, we describe a no...
Date: February 14, 2023 Time: 10:00am (PST), 1:00pm (EST), 7:00pm (CET) The dorsal pontine tegmentum (PnTg) is part of the Pons, the largest section of the brainstem. It is a complex region...
Date: February 09, 2023 Time: 9:00am (PST), 12:00pm (EST), 6:00pm (CET) Monoclonal gammopathies (MGs) comprise a broad set of diseases involving the abnormal clonal proliferation of plasma c...
Date: February 08, 2023 Time: 9:00am (PST), 12:00pm (EST), 6:00pm (CEST) Understanding cell-to-cell interactions in a tumor microenvironment are increasingly challenging due to the complexit...
Date: January 31, 2023 Time: 10:00am (PST), 1:00pm (EST), 7:00pm (CEST) Immunohistochemistry (IHC) is a standard technique for scientists and pathologists to detect antigens. Examining one o...
Date: January 26, 2023 Time: 10:00am (PST), 1:00pm (EST), 7:00pm (CET) In this case-based presentation, we will describe the most common pitfalls in laboratory testing that healthcare provid...
Date: January 26, 2023 Time: 8:00am (PST), 11:00pm (EST), 5:00pm (CET) NanoString’s GeoMx® DSP allows for the characterization of spatial distribution and abundance of proteins and...
Date: January 17, 2023 Time: 9:00am (PST), 12:00pm (EST), 6:00pm (CET) As SARS-CoV-2 infections continue to ebb and flow, other respiratory viruses have made a big comeback on the world stag...