Vice President, Discovery Chemistry at ChemPartner
FEB 24, 2021 3:00 PM PST
PROTACs: A Chemistry Journey of Protein Degraders
Presented at:
Drug Discovery & Development Virtual Event Series 2021
Speaker
Abstract
This talk reviews the advances in the field of Proteolysis Targeting Chimeras (PROTACs). It is divided to five topics: (1) Ligand-induced Target Protein Destabilization; (2) Small-Molecule Ligands for E3 Ubiquitin Ligases; (3) PROTACs Inducing Degradation of Nuclear Hormone Receptors; (4) PROTACs Inducing Degradation of Kinases; and (5) Miscellaneous PROTACs.
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