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The CRISPR revolution has begun and shows no signs of slowing down. CRISPR-Cas nuclease-based genome editing strategies hold great promise for the treatment of genetic disorders. However, a...
While clinical microbiology laboratories are pivotal in the identification and handling of infectious diseases, the microbiology lab environment is rapidly changing. Conventional testing met...
NanoCellect will discuss the importance of cell sample preparation in order to obtain good quality sequencing data with 3’ RNA-Seq as well as cell sample preparation in order to obtain...
Many of the most debilitating and life-threatening diseases are associated with the central nervous system. Some, such as neurodegenerative diseases, predominately afflict our aging populati...
Many direct immunoassays in use today for testosterone analysis are little better than a guess at the low levels that are sometimes required. This has led many clinical societies to adv...
Recent FDA approval of the first Chimeric Antigen Receptor T cell (CAR-T) therapy offers cancer patients more promise than ever for curative effects. However, many technical challenges in T c...
Genome Engineering allows the easy manipulation of genomes down to the nucleotide level. Targeted deep sequencing enables the detection and quantification of low-frequency editing events. Ho...
CRISPR (clustered regularly interspaced short palindromic repeats) RNA and CRISPR-associated genes (Cas) assemble into RNA-guided surveillance complex that targets foreign nucleic acids for d...
The study of a single cell, the fundamental unit of our complex bodies, has become an important field in cellular biology, and researchers are using single-cell analysis to shed new light on...
Neuroscience is experiencing an exciting era of integrating novel materials and tools to record neural activity made possible through significant advances in materials science, electrical en...
In this webinar, we will be discussing some of our most recent testing using our Cas9 proteins, Cas9 RNP nickases in a variety of human cell types, including primary T-cells. Cas nucleases wh...
Dr. Koenitzer will present an overview of her current research in immune suppression. After a brief introduction to the MILLIPLEX® multiplex immunoassay portfolio, Dr. Koenitzer will dis...
The discovery of the CRISPR/Cas9 system has transformed research and now allows straightforward alterations in the genome and can be exploited to introduce changes to mimic diseases. This pre...
The nature of work in the clinical core lab has changed over the years from beakers of liquids, specimens and compounds on countertops to sophisticated equipment with prepackaged reagents and...
Adolescence is a critical period for the developing brain, and binge drinking during this neuromaturation can result in enduring abnormal brain function and behavior. Repeated adolescent bin...
High-throughput sequencing technology such as RNASeq and whole genome sequencing has enabled deep characterization of health and disease states. Biomarker discovery by these means has only h...
Since the introduction of single cell sequencing techniques to the genomics community, interest in its use has grown exponentially and the number of single cell publications has exploded. Th...
Breast cancer is the most frequently occurring form of cancer in women. While 5-year survival rates for localized disease approach 99%, cases of advanced breast cancer have a much poorer pro...
Multiplex immunofluorescence IHC is a powerful technique to address the increasing research needs in immuno-oncology to better understand the tumor microenvironment. In this webinar, we will...
As ‘omics research advances, separations data such as chromatograms and nuclear magnetic resonance (NMR) spectra are being used as direct inputs to machine-learning algorithms ranging...
Much has been said about the promise of Next Generation Sequencing (NGS) to revolutionise diagnosis of rare diseases, and there are many examples of success in this arena. However, the majori...
Acute and chronic pain are often managed with drug therapy, which may include extended use of drug classes such as opioids and benzodiazepines. Pain does not go away, and may intensify...
Medical laboratories are an integral part of the healthcare system. They supply crucial diagnostic data that underpins disease detection, patient care, and public health management....
The human race, like all macrobiological life, evolved in a sea of microbes. There was no way to keep the bacterial and archaeal hoards at bay, so instead life evolved mechanisms to live with...
Since its initial description more than 70 years ago, autism spectrum disorder (ASD) has been diagnosed more frequently in boys. However, we remain unsure of why males are affected in greater...
We have developed 3D-shaped hydrogel microparticle platforms to capture cells, as well as isolate and label their secretions. These “lab on a particle” systems enable sorting cel...
CRISPR-Cas9 based gene editing is a powerful tool which can induce heritable mutations at desired genomic loci without leaving transgenic trace in plants. Here we constructed a robust, multip...