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Antimicrobial resistance (AMR) detection and surveillance is a high priority in healthcare and environmental settings for the safety of both patients and the general public. However, working...
Virginia will discuss work on single-trial analysis of EEG signals during episodic memory tasks. They develop single-trial classifiers to predict whether people will remember pictures from E...
Molecular diagnostic assay development and design is no simple task, and several factors affect the performance and usability of a test. Diagnostic companies can enhance assay stability and...
Currently laboratory research demands more application versatility and certainty for metabolite identification, targeted compound screening, and the ability to identify true unknown compound...
A central goal in single-cell cancer research is to identify phenotypically distinct cells that have prognostic significance for patients. This need is acute in brain tumor glioblastoma, whe...
10:00am PT, 12:00pm CT, 1:00pm ET: Welcome 10:15am PT, 12:15pm CT, 1:15pm ET: Digital PCR for minimal residual disease research and cancer research Dr. Christopher E. Mason Professor of Geno...
Spatial analysis of protein or gene expression is vital to understanding the distribution, phenotypes, and interactions between cells within tumor microenvironment (TME). Traditionally, mult...
Neoantigen vaccines are a type of personalized cancer vaccine. While clinical trials have shown promising results, it is important to note that neoantigen vaccines are still in the early sta...
In the last decade or so, R&D into the human microbiome-based therapeutics and diagnostics has accelerated the widespread availability of next-generation DNA sequencing technologies that...
Measuring the shear rheology for highly temperature sensitive materials is challenging. Material characterization tools are slow compared to industrial processing. Using numerical simulation...
Tandem repeats are hard to assess but important regions on the human genome. There are around 200 pathogenic and phenotypic tandem repeats, which are often ignored by standard analysis. Furt...
To identify genetic variants in archival human samples, researchers need a powerful NGS platform that can accommodate input DNA and RNA that is often low quality and/or low quantity. This ch...
The state of healthcare today and tomorrow can be best described as complex and unpredictable. From chronic diseases to neurodegenerative diseases such as Alzheimer’s, infectious disea...
Comprehending the mechanism behind human diseases with an established heritable component represents the forefront of personalized medicine. Nevertheless, numerous medically important genes...
Extrachromosomal circular DNA (eccDNA) comprises products of genomic recombination that cause somatic changes in gene length and sequence. These circular molecules are derived from canonical...
The difficulties in making an accurate diagnosis, the workload in terms of time and the small number of pathologists represent significant problems in laboratory routine. From this perspecti...
The FDA submitted its final rule regarding laboratory diagnostic tests (LDTs) on May 6, 2024. While it allows for 4 years for compliance and it is currently being disputed by various associa...
One of the most common pathologically relevant mutated variants of ALK-2 (activin receptor-like kinase-2) has a point mutation (R206H) in its Ser/Thr kinase domain that promotes uncontrolled...
The highly competitive nature of academic environments might seem to suggest that success can only be obtained at the cost of taking good care of oneself. However, sacrificing self‐care can...
Current cancer management follows a multipronged approach that include surgery, radiation, and chemotherapy. There is a pressing need for a platform technology to provide precision chemother...
As obligate intracellular pathogens, viruses require host-derived nucleotides, amino acids, and lipids, among others, and the bioavailability of these metabolites can restrict or promote vir...