Learn about the latest medical breakthroughs by participating in webinars on topics surrounding disease, prevention and treatment in accordance with the latest research in health and medicine. Updates encompass a biological, psychological and sociological understanding of health.
Parkinson’s disease (PD) belongs the group of synucleinopathies characterized by progressive aggregation of the neuronal protein alpha-synuclein (asyn). Diagnosis and evidence of disea...
Learning Objectives: 1. Review the basic principle of 3D microscopy. 2. Recognize the pathophysiology of Parkinson disease. 3. Demonstrate knowledge on how alpha-synuclein aggregates spread...
The advancement in ultra-sensitive immunoassays and highly specific immunoprecipitation mass spectrometry (IPMS) methods, complimented by an increasing number of well-characterised research...
The Brain Behavior Quantification and Synchronization (BBQS) program is a basic research effort in the NIH BRAIN Initiative to develop new tools and approaches in support of a more comprehen...
Protein misfolding and aggregation are key features observed in numerous neurodegenerative conditions, such as Alzheimer's and Parkinson's disease. The oligomers formed during the ag...
This talk will present the methodology of using the guided ultrasonic waves generated by the rodent to track its physiology, behavior, and psychological state. When behaving in an environmen...
We are developing the three-banded panther worm Hofstenia miamia as a new model system for neuroscience. Hofstenia is a rare, lab-tractable member of a lineage of early-branching marine inve...
The study of psychopathology is changing with the advent and pervasive use of smartphones, wearables, and connected devices together with significant advances in brain imaging. These new ave...
A central goal for neuroscience is to understand how our brains process information in real life, such as faces during natural social interactions. While we have gained important knowledge u...
The ability to record every spike from every neuron in a behaving animal is one of the holy grails of neuroscience. Here, Alison Hanson discusses a collaborative effort aimed at coming one s...
Behaving animals continually reconcile the internal states of their neural circuits brain-wide with incoming sensory and environmental evidence to evaluate when and how to act. The brains of...
To make movement and foraging decisions in a naturalistic environment, multiple neural populations must work synergistically to produce successful actions. These decisions span multiple scal...
Virginia will discuss work on single-trial analysis of EEG signals during episodic memory tasks. They develop single-trial classifiers to predict whether people will remember pictures from E...
Individuals with substance use disorders often show impaired sensitivity to reward value. However, it is not clear whether such impairment impacts reward-related decision making and whether...
Studying motor behaviors can reveal fundamental principles of the brain and mind. This presentation focuses on our work towards developing the hardware and computational tools that will allo...
With the internet, society has been exposed to puzzling and exquisite animal behavior, while neuroscience has vastly concentrated on a few inbred animal models studied in trained unnatural s...
A core goal of neuroscience is to understand how the brain adaptively orchestrates movements to execute complex behaviors. Quantifying behavioral dynamics, however, has historically been pro...
Many nonhuman primate species show sex differences in behavior, which suggests that there may also be sex differences in brain organization. In order to better understand the evolution of se...
How do the cognitive and physiological traits of individuals translate into real-world group dynamics? There is an empirical and theoretical gap between understanding individual-level proces...
Our ability to record large-scale neural and behavioral data has substantially improved in the last decade. However, the inference of quantitative dynamical models for cognition and motor co...
Transdisciplinary knowledge producing teams (TDKPTs) dedicate their efforts to solving wicked problems. Successful TDKPTs embody characteristics of complex adaptive systems (CAS) and exempli...
Social interactions are essential for the survival of social animals. Across species the medial prefrontal cortex (mPFC) has been identified as a hub of social cognition. In mouse models we...
Infant motor development is measured clinically using short, subjective, observational scales. While these scales are useful, they have limitations. They provide us with a “snapshot&rd...
Drug discovery programs require a robust panel of models and assays to identify and validate drug targets, support compound optimisation, and run mechanistic studies. Fully human in vitro mo...
DBS for obsessive-compulsive disorder (OCD) achieves clinical benefit in 66% of treatment-resistant patients. However, there is still a lack of a fundamental understanding of the neurophysio...
Brain organoids are self-assembled three-dimensional cellular aggregates with cell types and tissue architectures that resemble the embryonic human brain. As they recapitulate many key featu...
Explore how proficiency testing helps labs ensure accuracy, meet regulations, and identify testing issues to improve performance...
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