Follow a curation of discoveries and updates in immunology focusing on immune responses to infectious disease, structure and function, and developments in the defense against infection by watching and engaging in these webinars.
Since late 2020, several prominent SARS-CoV-2 variants of concern have emerged, harboring specific mutations which increase viral transmissibility Delta variant) and which appear to reduce t...
Coronavirus Immunotherapeutic Consortium (CoVIC) is an international effort to conduct side-by-side, apples-to-apples comparisons of leading therapeutic antibody candidates against the SARS-...
Single-cell RNA sequencing (scRNA-seq) is an important technology that reveals gene expression differences between different cell types. Yet scRNA-seq data can be challenging to analyze and...
In this session we will use a set of reads enriched for viral sequences and sequences from wastewater treatment plants. Specifically the aim is to assemble whole SARS-CoV-2 genomes from such...
The immune system evolved to protect us against pathogen invasion and to maintain tissue homeostasis. Fundamental for these functions are the interferons (IFNs), a group of cytokines that be...
Infection with human immunodeficiency virus (HIV)-1 compromises the immune system and causes in about half of the affected individuals neurological and neurocognitive complication categorize...
Natural killer (NK) cells, immune cells with an innate ability to recognize and eliminate cancer cells, have emerged as attractive effectors in immunotherapy, owing in large part to their ab...
While providing indispensable insight into immune processes, the live cell imaging of immune cells poses unique challenges due to their non-adherent nature. Suspension cells such as immune c...
Over years, HMGB1 has increasingly attracted the attention of all kinds of researchers. It is one of the most intriguing molecules within the complete arsenal of proteins of the innate immun...
Tumor phenotypes are dictated not only by the neoplastic cell component, but also by the tumor microenvironment (TME), which is inherently immuno-suppressive, is equipped to hamper effector...
Advancements in immuno-oncology have been moving at an ever-quickening pace. From the development of new CAR-T therapies to a better understanding of the mechanism of action of monoclonal an...
Despite the immense promise of cancer immunotherapies, significant challenges have been mounting to overcome treatment resistance and to improve efficacy. Strategies such as the combination...
Molecular diagnostic tests are currently used for infectious disease testing due to the superior sensitivity and specificity that can be obtained. Due to the success that has been obtained w...
Prostate cancers are considered immunologically ‘cold’ tumors given the very few patients who respond to checkpoint inhibitor therapy (CPI). Recently, enrichment of interferon st...
Learning Objectives: 1. Define applications of approved and experimental (multiplexing IF) biomarker assessment in Immuno-Oncology 2. Define bottlenecks and areas of improvement to current t...
Plant-infecting viruses cause significant losses to agriculture, including to staple crops such as wheat, maize, and rice. Preventing and managing endemic and emerging plant diseases is an o...
The Coronavirus disease 2019 (COVID-19) pandemic poses an unprecedented challenge for public health, which is caused by infection of severe acute respiratory syndrome coronavirus 2 (SARS-CoV...
This webinar will highlight the research solutions that Miltenyi Biotec has to offer for those investigating the roles of Tregs, NK cells, and Macrophages in the context of the tumor microen...
Cells in their natural environment are surrounded by a complex extracellular matrix that provides structure and functional cues to the surrounding cells. Hydrogels can be used to approximate...
Immune checkpoint blockade has revolutionized the treatment for patients with cancer. Great efforts remain to better understand resistant mechanisms to treatment as well as means to improve...
Severe acute respiratory syndrome coronavirus (SARS-CoV-2) is a novel virus that causes COVID-19 and has considerable variability in clinical outcomes among infected patients. The GENCOV stu...
Primary resistance to CD19-directed chimeric antigen receptor T-cell therapy (CART19) occurs in 10% to 20% of patients with acute lymphoblastic leukemia (ALL); however, the mechanisms of thi...
We recently determined that concurrent inhibition of autophagy, using the lysosomal inhibitor chloroquine (CQ), and of ERK, using a small molecule ERK inhibitor (ERKi), synergistically suppr...
Discover how experience in utilizing a digital lab platform can elevate research workflows. Margriet will share insights, practical strategies, and success stories that demonstrate the benef...
Over the past 10 years, we have come to a greater understanding of the pathogenesis of men who succumb to prostate cancer. One critical aspect is the role of molecular drivers in patients wi...
The future of cancer care is contingent on better understanding of molecular, clinical, and outcome data. This can be achieved by leveraging collaborative affiliations and networks locally a...
Since late 2020, several prominent SARS-CoV-2 variants of concern have emerged, harboring specific mutations which increase viral transmissibility Delta variant) and which appear to reduce t...
