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Biosearch Technologies

Locked nucleic acid (LNA) probes | Biosearch Technologies

These dual-labelled hydrolysis probes include up to seven LNA bases (RNA bases “locked” in the C3′-endo conformation) in the probe. Each LNA insertion increases the Tm of the probe-target duplex by 2-8 °C, stabilising the duplex, which enables a shorter probe design, improved sequence specificity and assay sensitivity. LNA probes offer precise Tm control in SNP genotyping and gene expression assays.

Supporting Documents


Whitepaper

A probe for every occasion: A how-to guide for qPCR probe selection

Whitepaper

Optimising and validating multiplex qPCR assays

Whitepaper

How the pros build a better qPCR assay

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ABOUT THE COMPANY

Biosearch Technologies is the comprehensive genomics portfolio from LGC, providing products and services for genomic analysis that support mission critical applications for global customers in agrigenomics and human healthcare.

 

The portfolio offers integrated tools and technologies to accelerate sample preparation, amplification,...

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