Creative Biolabs is the leading custom service provider with extensive experience in various antibody production and engineering fields.
This kit provides a complete lentivirus packaging system to produce anti-NKG2DL (NKG2D receptor) h(4-1BB-CD3_) CAR lentivirus, which enables CAR-T cells generation to target Human NKG2DL. It contains plasmids that express all the viral proteins necessary, and CAR detection reagent, providing a full set of reagents for CAR lentivirus packaging and CAR expression evaluation. The expressed anti-NKG2DL CAR lentiviruses are HIV-based, VSV-G pseudotyped lentiviral particles that are ready to be transduced into almost all types of mammalian cells. These viruses constitutively express the scFv portion of anti-NKG2DL (NKG2D receptor) linked to 3nd generation CAR containing CD28, 41BB and CD3_ signaling domains. CAR detection reagent can be used to detect the positive expression rate of CAR-T cells after lentiviral transduction.
Creative Biolabs is the leading custom service provider with extensive experience in various antibody production and engineering fields.