Many oncology patients do not receive the most effective targeted treatments because of challenges associated with implementation of a personalized medicine approach. Despite a lengthy history of targeted treatment availability in advanced non-small cell lung cancer (aNSCLC), a recent study found that 644 of every 1,000 newly diagnosed aNSCLC patients (64.4%) did not receive a personalized treatment due to clinical practice gaps in the delivery of precision oncology. Patients are lost at various steps along the precision oncology pathway because of operational inefficiencies, limited understanding of biomarkers, inappropriate test result usage, and access barriers. An increased understanding of the impact of each clinical practice gap can inform strategies to improve the delivery of precision oncology.
Learning Objectives:
1. List the clinical practice and policy challenges related to diagnostic testing and the delivery of appropriate targeted therapies leading to a failure of patients to receive precision oncology strategies.
2. Discuss what impact each clinical practice gap has on the population level delivery of precision oncology.
3. List the policies and practices that can help assure optimal and equitable delivery of appropriate high value personalized medicines.