Hepatobiliary cancers, including hepatocellular carcinoma (HCC) and gallbladder cancer (GBC), are strongly linked to chronic inflammation. Recent research using the Olink PEA Technology suggests that circulating immune-related proteins may serve as powerful biomarkers for identifying individuals at risk.
In this session, we’ll discuss findings from large hepatitis B virus (HBV)- and hepatitis C virus (HCV)-positive cohorts, including patients with advanced fibrosis or cirrhosis, highlighting proteins such as ICAM-1, CXCL11, HGF, CFHR5, and SCF, and their associations with cancer risk. We’ll also explore population-specific differences, including inflammatory profiles among women with Mapuche ancestry, offering new insights into risk stratification for gallbladder cancer.
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