What Does Quality Mean to You? - Analytical Tools for Defining a Complex Botanical

The use of Δ8-THC in consumer products has caused safety concerns in the US. Though Δ9-THC is the main intoxicating component in the cannabis plant, its isomer, Δ8-THC, naturally occurs in the cannabis plant at low levels. The Δ8-THC used in consumer products is typically produced from hemp-derived CBD which many consider legal under the 2018 US Farm Bill. Regulations governing the use of synthetic components derived from hemp are not clearly addressed which has created a growing market for Δ8-THC production and use. The conversion of CBD to Δ8-THC requires harsh conditions leading to multiple reaction byproducts which need to be characterized to enhance understanding of the chemical components produced. Considering that much is unknown about product composition, how can industry stakeholders determine quality? What role does analytical chemistry play? This presentation will describe how questions regarding cannabis quality and safety can be explored using various chromatography, mass spectrometry, and ion mobility technologies.

Learning Objectives:

1. Explain how the definition of quality varies throughout the cannabis supply chain.

2. Discuss how different types of analytical tools can aid in cannabis characterization.

3. List resources and stakeholder groups that facilitate cannabis science advancement.