Using Prostate Cancer Exome Data to Identify Candidate Genes

In this presentation, exome data from individuals with prostate cancer will be aligned against an annotated reference human genome and SNPs will be identified using DNASTARs SeqMan NGen software. SNPs and associated genes from disease samples will be compared against numerous control samples and a list of genes known to be implicated in prostate cancer or other cancers to identify additional candidate SNPs and genes in sample data. All work will be done using DNASTARs Lasergene Genomics Suite software, which is available on desktop computers or on the Amazon Cloud. The integration of these capabilities within one software package facilitates fast, comprehensive analysis, helping researchers move quickly from raw next-generation sequence data to informative results.