The complexity and heterogeneity of protein therapeutics present significant challenges in biologics discovery, as post-translational modifications (PTMs) and sequence variants can affect product quality, safety, and efficacy. Mass Spec (MS) has emerged as a powerful tool for structure and function analysis with unmatched precision and high-throughput (HTP) capabilities.
This webinar will showcase advanced MS methodologies, such as HTP Intact Mass, peptide mapping, and glycan analysis, for both qualitative physicochemical characterization and quantitative analysis for target validation and PK assessment. Real-world case studies will demonstrate how these approaches deliver comprehensive structure and function insights, driving more definitive biologics discovery and optimization.
You’ll discover how MS can: