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AAV peptide display libraries allow for the generation of novel variants capable of high-level transduction. We previously described an AAV peptide display library combined with a sensitive...
As the use of engineered cells for the production of numerous research and clinical applications increases, the need to monitor multiple markers representing the stability and quality of the...
The microenvironment of many solid tumors impedes many immunotherapeutic treatments by inhibiting the effector functions of many classes of anti-tumor immune cells, including effector T cell...
The Genomes2People Research Program (G2P), led by Robert Green at Brigham and Women’s Hospital, the Broad Institute, Ariadne Labs, and Harvard Medical School, conducts research to acce...
There are currently several different FDA approved radiopharmaceuticals being used in both large academic and small practice settings to accurately stage and identify local and metastatic pr...
Molecular testing of NCSLC biopsies is extremely important in the care and management of these patients. However, NCSLC biopsies are typically very small and require multiple types of analys...
I will discuss and present data and viewpoints so discuss the current situation with THC Lab shopping, it’s impact on the industry from growers through labs to end-users, how we got he...
Neutrophils are the most abundant immune cells in human blood and are crucial for host defense against bacterial and fungal infections. Neutrophils are made mainly in the bone marrow from wh...
Hypoxia is pervasive across human cancer and its association with poor outcomes and aggressive malignant phenotypes has been increasingly appreciated. Previously, we and others described how...
NGS technology has grown leaps and bounds in reproductive genetics field. Infertility is on the rise and with the mushrooming of so many IVF clinics in our country and increasing number of I...
Since its discovery in late 2019 the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has created a global pandemic of coronavirus disease 2019 (COVID-19). As of July of 2022, mo...
Over the last decade we have witnessed tremendous advances in our understanding of the underlying molecular alterations in human cancer. This has stimulated excitement for our ability to deve...
Mouse models have been essential for establishing the role of the T cells in anti-tumor responses, but they have limited utility in translational studies for the testing of candidate therape...
To determine efficacy of specific complementary therapies to advance evidence-based, integrative healthcare, the complementary modality should first be introduced to stakeholders to determin...
Coronavirus research cannot wait. As we know researchers around the world are diligently working to gain a better understanding of the novel coronavirus with the goal of rapidly identifying...
The nervous system of social species has evolved to perceive and evaluate signals within a social context. Social information therefore must impact how the brain processes information, yet l...
Learning Objectives: 1. Discover how Genetics is not the major determinant of chronic diseases and cancers; human microbiome and nutrition heavily contribute to their onset and progression....
Mild traumatic brain injuries (mTBIs) are a prevalent health issue in North America. There is increasing pressure to utilize ecologically valid models of closed-head mTBI in the preclinical...
Protein production is a multi-billion dollar industry, with applications in pharmaceuticals, industrial enzyme use (eg in laundry detergent), and biomaterials. Bacteria are receiving renewed...
Traditional hybridoma and phage display methods have failed to yield therapeutic antibodies against difficult targets like most GPCRs and ion channels. This presentation will introduce Berke...
Design and interpretation of genome sequencing assays and data in both clinical diagnostics and research labs is complicated by an inability to identify information from the medical literatu...
The structure of N-linked glycans can play a critical role in the pharmacology of therapeutic proteins, potentially affecting immunogenicity, pharmacokinetics and pharmacodynamics. This make...
AAV peptide display libraries allow for the generation of novel variants capable of high-level transduction. We previously described an AAV peptide display library combined with a sensitive...
