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To make movement and foraging decisions in a naturalistic environment, multiple neural populations must work synergistically to produce successful actions. These decisions span multiple scal...
Rapid screening and speed of scale-up in protein therapeutics are critical factors in today’s biotech and pharma workflows. The ability to swiftly develop novel therapies often depends...
Traditional hybridoma and phage display methods have failed to yield therapeutic antibodies against difficult targets like most GPCRs and ion channels. This presentation will introduce Berke...
Stem cells respond to both physical and biochemical changes in their stem cell niche. An ideal scaffold for tissue engineering application should mimic the microenvironment for natural tissu...
Jeff Borgia, Ph.D. is the Director of the Rush Cancer Center Biorepository, where he oversees the collection and annotation of patient specimens in support of ongoing translational research...
Microtubule plus-end tracking proteins (+TIPs) play key roles in the regulation of microtubule dynamics in vivo. These proteins bind to and regulate microtubule “plus‐ends”, whic...
Though AsCas12a fills a crucial gap in the current genome editing toolbox, it exhibits relatively poor editing efficiency, restricting its overall utility. In collaboration with Integrated D...
Measuring the shear rheology for highly temperature sensitive materials is challenging. Material characterization tools are slow compared to industrial processing. Using numerical simulation...
The regions of our genome responsible for encoding the genes that regulate our immune response are some of the most complex and polymorphic known. This complexity encompasses multiple types...
Rather than being famous in gene editing field only, by revealing the collateral cleavage activity of Cas12a, Cas13a, Cas14 effectors, and more, Clustered Regularly Interspaced Short Palindr...
Tuberculosis (TB), caused by the pathogen Mycobacterium tuberculosis (Mtb) remains one of the leading causes of morbidity and mortality worldwide. This presentation will summarise the epidem...
Traditional methods for pathogen detection are often expensive and time-consuming and requires a well-equipped laboratory. Here we present a low-cost, deployable paper-based biosensor device...
The Irvine CubeSat STEM Program (ICSP) is a collaboration between Irvine Public Schools Foundation, and Irvine and Tustin Unified school districts that provides teams of students from all si...
Carbon dioxide emissions, known to exacerbate climate change, have been increasing rapidly over the past century. One strategy to alleviate this issue is carbon capture and utilization (CCU)...
Prompt and early diagnosis of sexually transmitted infections (STIs) is important to enable appropriate treatment and help prevent further transmission....
Unique physical, chemical, and optical phenomena arise when materials are confined to the nanoscale. We are accustomed to making observations for the behavior of living systems on a macrosco...
De Novo Software has been a leading provider of cytometry analysis tools since 1998 and provides data analysis tools for both flow and imaging cytometry. FCS Express 7, De Novo Software&rsqu...
Surface plasmon resonance is a real-time and label-free technique that offers low sample consumption and high throughput when compared to other biophysical techniques and has been widely ado...
Traditional liver perfusion procedures – used to isolate hepatocytes – are difficult to perform and require extensive training, steady hands and long-standing experience. In this...
High volume clinical MS proteomic evaluation of plasma samples enriched for exosomes offering a real-time and non-invasive perspective of changing maternal and fetal tissues....
Mass spectrometry-based proteomics is a powerful technique for the analyses of thousands of proteins, fueling biomarker research and drug discovery. With the rich complex data from each prec...
In recent years in vivo CNS dosing has gone from being a relatively uncommon modality to one that is fairly standard. However, bringing this administration route into maturity requires an un...
G Protein Coupled Receptors (GPCRs) are therapeutic targets for many medications used to treat a variety of disease states. A large number of genetic variants have been identified in the gen...
Myeloid neoplasms are a group of heterogeneus disorders originating from the neoplastic transformation of a pluripotent hematopoietic progenitor cell. Following the acquisition of somatic mu...
To make movement and foraging decisions in a naturalistic environment, multiple neural populations must work synergistically to produce successful actions. These decisions span multiple scal...
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