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In recent years in vivo CNS dosing has gone from being a relatively uncommon modality to one that is fairly standard. However, bringing this administration route into maturity requires an un...
Learning Objectives: 1. Explain how obesity impacts the survival of pediatric patients with specific subtypes of leukemia. 2. Describe how obesity impacts T-cell function in pediatric popula...
Acute T-cell mediated rejection (TCMR) is the most frequent complication after liver transplantation (LT), which can affect up to 50% of LT recipients in the first 5-year post-transplant. Li...
Thermo Fisher Scientific have spearheaded the development and democratization of next-generation sequencing, a technology that has fueled research in precision oncology and will play a key p...
In genomics, as in life, you need to be in the right place at the right time, and you need integrity, to be credible. Since the availability of the human genome sequence, there's been an...
NGS is still perceived as a complex, hard to implement and validate method that requires highly experienced people. Outsourcing next-generation sequencing (NGS) testing could be an option to...
Brain malignancies can either originate from within the CNS (gliomas) or invade from other locations in the body (metastases). A highly immunosuppressive tumor microenvironment (TME) influen...
Immunohistochemistry (IHC) has been an indispensable tool for daily pathology practice. Multiplex designs have further facilitated its utility with improved efficacy. Several techniques of m...
Genetics may influence experience with cannabis and CBD. With increased access to legal cannabis and the research community expanding their focus on the medicinal uses of cannabinoids, more...
Lateral flow assays (LFA) are simple diagnostic tools that can be used to detect a variety of biomolecules that include biomarkers, pathogens, and environmental contaminants. Many industries...
Join this year's poster presenters in the Poster Hall during the Poster Networking Hour, Wednesday, March 6th, from 10:00 AM –11:00 AM PST, to chat live about their posters and lat...
The next-generation sequencing (NGS) technologies have led to shifting paradigms for hereditary cancers genetic testing. With the increasing sensitivity of new technologies and the reduction...
Cancer, as a disease, starts with a change in the genome that results in the downregulation of genes involved in "normal" cell behavior. This genetic change can either be induced b...
Learning Objectives: 1. Classify the obstacles to successful manufacturing of antigen-specific T-cells in immunotherapy. 2. Highlight the effects of CD45RA+ subsets in expansion of antigen-s...
November 13, 2020 6:00 PM PST | November 14, 2020 10:00 AM SGT
LED illumination has become more prominent in microscopy for both fluorescence and transmitted applications over the past few years. Today, LEDs provide many benefits over mercury and metal...
Within the kidney, the glomerulus is the structure in charge of the renal ultrafiltration. Loss of glomerular function leads to renal damage and could end with irreversible damage. The major...
Protein misfolding and aggregation are key features observed in numerous neurodegenerative conditions, such as Alzheimer's and Parkinson's disease. The oligomers formed during the ag...
The integration of scientific instruments and robotics is often a barrier for physical scientists developing new autonomous discovery capabilities. At Argonne National Laboratory, the Rapid...
Despite the remarkable clinical efficacy of chimeric antigen receptor (CAR) T cells in hematological malignancies, only a subset of patients achieve a durable complete response. Furthermore,...
Chimeric antigen receptor (CAR) T-cell therapy has been extremely successful in treating relapsed/refractory B-cell malignancies, with six CAR T-cell products now FDA approved. Unfortunately...
We will discuss the Digital LightCycler System, a digital PCR (dPCR) system for DNA and RNA with 6-color capability for flexible, multiplexed biomarker detection. With advances in sensitivit...
Simple and sensitive nucleic acid-based molecular detection plays a crucial role in the early diagnosis of infectious diseases and the rapid screening of cancers. CRISPR technology has recen...
Chimeric antigen receptor (CAR) T cells have demonstrated significant success in treating relapsed or treatment-refractory hematologic malignancies in the clinic, inducing remissions in 70-9...
This is a technical talk. Its objective is to provide details of virus sequencing, using SARS-CoV-2 as an example. Knowing the details, strengths, and limitations of virus sequencing will en...
In recent years in vivo CNS dosing has gone from being a relatively uncommon modality to one that is fairly standard. However, bringing this administration route into maturity requires an un...
