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Embarking on the journey of LIMS data migration, whether it's transitioning to a new LIMS or upgrading to a more advanced version, may initially appear as a straightforward task. However...
Learning Objevtives: 1. Demonstrate Knowledge with gene editing, microfluidics and non-viral delivery methods. 2. Review the uses of a low-volume high-throughput transfection platform for ge...
This talk will focus on doing method validation work in an environment where data is gathered from laboratory information system and chromatography data system. We’ll see how these sys...
Validation of computerised systems is a regulatory requirement for both GMP and GLP laboratories. Although computerised system validation (CSV) has been required for over 40 years, the appro...
The 21st century brought with it an unprecedented number of global and regional economic and political crises, giving rise to a new generation of conflicts in which novel technological, biol...
Laboratories use the same laboratory equipment they invested in for COVID testing to perform PGx testing. With COVID testing reimbursement dropping, many laboratorians are considering implem...
The practice of diagnostic pathology has gone through a disruptive transformation in which multiple tools such as digital imaging, advanced artificial intelligence algorithms, and computer-a...
Brian Uzzi presents two studies on innovation in science. Study one examines conditions favoring the generation of innovative, high impact ideas and study two examines the conditions that ef...
The rapid growth of technologies capable of comprehensively collecting, managing, and allowing us to gain an in-depth picture of the brain, nervous system, and behavior across diverse spatia...
Learning Objectives: 1. Describe language disturbances in schizophrenia and its risk states. 2. Describe face expression disturbances in schizophrenia and its risk states. 3. Describe ethica...
The nervous system of social species has evolved to perceive and evaluate signals within a social context. Social information therefore must impact how the brain processes information, yet l...
Laboratories are required to participate in proficiency testing (PT). PT is a powerful tool for laboratories to learn about their own testing performance and discover potential issues with t...
Parkinson’s disease (PD) belongs the group of synucleinopathies characterized by progressive aggregation of the neuronal protein alpha-synuclein (asyn). Diagnosis and evidence of disea...
Learning Objectives: 1. Review the basic principle of 3D microscopy. 2. Recognize the pathophysiology of Parkinson disease. 3. Demonstrate knowledge on how alpha-synuclein aggregates spread...
A central goal for neuroscience is to understand how our brains process information in real life, such as faces during natural social interactions. While we have gained important knowledge u...
Recent advances in gene editing has allowed the generation of advanced rodent research models, mimicking some aspects of human conditions. For neurodegenerative disorders such as Alzheimer&r...
Brain organoids are self-assembled three-dimensional cellular aggregates with cell types and tissue architectures that resemble the embryonic human brain. As they recapitulate many key featu...
We are developing the three-banded panther worm Hofstenia miamia as a new model system for neuroscience. Hofstenia is a rare, lab-tractable member of a lineage of early-branching marine inve...
The study of psychopathology is changing with the advent and pervasive use of smartphones, wearables, and connected devices together with significant advances in brain imaging. These new ave...
DBS for obsessive-compulsive disorder (OCD) achieves clinical benefit in 66% of treatment-resistant patients. However, there is still a lack of a fundamental understanding of the neurophysio...
The ability to record every spike from every neuron in a behaving animal is one of the holy grails of neuroscience. Here, Alison Hanson discusses a collaborative effort aimed at coming one s...
Behaving animals continually reconcile the internal states of their neural circuits brain-wide with incoming sensory and environmental evidence to evaluate when and how to act. The brains of...
Many nonhuman primate species show sex differences in behavior, which suggests that there may also be sex differences in brain organization. In order to better understand the evolution of se...
Protein misfolding and aggregation are key features observed in numerous neurodegenerative conditions, such as Alzheimer's and Parkinson's disease. The oligomers formed during the ag...
Robots are useful tools for studying the nervous system and its control of body mechanics because they can be used to perform experiments that would be difficult to perform with an animal. F...
Social interactions are essential for the survival of social animals. Across species the medial prefrontal cortex (mPFC) has been identified as a hub of social cognition. In mouse models we...
Infant motor development is measured clinically using short, subjective, observational scales. While these scales are useful, they have limitations. They provide us with a “snapshot&rd...
Embarking on the journey of LIMS data migration, whether it's transitioning to a new LIMS or upgrading to a more advanced version, may initially appear as a straightforward task. However...
